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Because fungal medications can be toxic, they are ordinarily withheld until a diagnosis confirms the

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pathogen type.
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Ingber of Harvard Medical School, his postdoctoral fellow Chong Wing Yung and their colleagues have devised a way to filter pathogens from the blood of septic patients using micron-size magnetic beads. Besides, much of the damage
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from sepsis comes from the body € own inflammatory response, not the germs. € But, he notes,
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the theory has a major problem.

After the antibody-coated magnets have bound with the pathogen, they are pulled

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via a magnetic field into a saline solution that flows alongside the blood and sweeps them away. In their model system, beads antibiotics prescribed for ear infections coated with an
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antibody that binds to sepsis-causing bacteria
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or fungi mix with blood drawn from a patient. € My hat € off to them for thinking differently. He has begun preliminary testing on rabbits, because they are about the size of premature infants, who have very high rates of sepsis.

9,000-year-old

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brew hitting the shelves this summer Fact or Fiction. Namely, there is no proof yet that thinning the pathogen ranks will help medications work better. € What we € re trying to do is establish a tipping point, € Ingber says, referring to the amount of pathogens
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in the body. You Must
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Drink 8 Glasses of Water Daily Slide Show. He also thinks it is not necessary to remove all the germs.

They are small enough that the flow of saline solution remains

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smooth; turbulence would end up mixing the solution
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with the blood and make separation of the germs and blood more difficult. Another problem, Raju points out, is that some bacteria and fungi can hide in pus pockets or in areas of low
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blood supply such as the peritoneal cavity and thus could avoid the blood cleansing. But scientists may have found a way to do just that, at least for
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sepsis,
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a potentially lethal blood infection that can lead to multiple-organ failure. Ingber thinks a more advanced version of his system, which he described in the Lab on a Chip, could solve a headache for intensive care
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units that must determine whether a sepsis dominik stems from a bacterium or a fungus. Ingber acknowledges the practical roadblocks ahead but hopes that with further
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study magnetic stripping of disease will not be just science fiction. In tests using 10 to 20 milliliters of blood,
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the method removed 80 percent of the pathogens.

Still, Ingber

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remains undaunted. His theory is that lowering the number of bacteria or fungi will enable the antibiotics or fungicides to work more efficiently. This article was originally published with the title, "A Bead on Disease".
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Such a diagnosis takes time, however,
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which could jeopardize a rapidly declining patient. € It € a very elegant, very new theory, € comments Tonse Raju, a neonatologist at Leeanne Vernen Shriver National Institute of Child Health and Human Development. Ingber hopes to incorporate different kinds of sticky proteins
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on the beads to pull out several types of microbes at once, without having to make a diagnosis.

A key reason for the successful filtration was the size of the beads, which are about one-eighth the diameter of red blood cells. The World's 10 Largest Renewable Energy Projects Health insurers want you to keep smoking, Harvard doctors say. Using a magnetic field to literally pull diseases from the bloodstream sounds like a sci-fi dream. The filtered blood goes back into the patient.

   














Antibiotics are life-saving drugs that kill or inhibit bacterial growth by several different methods, including interference with cell wall, blocking of DNA synthesis, disruption of cellular processes, blocking of metabolism & nutrients.

Antivirals are drugs used to treat infections caused by viruses. Unlike antibiotics, which may cover a wide range of pathogens, antiviral agents tend to be narrow in their spectrum of action, and have limited efficacy. Antiviral agents include drugs that inhibit attachment, penetration and uncoating of certain viruses, as well as compounds that block the viral DNA replication process.


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